Key to symbols
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
2.8. Anticoagulants and protamine
2.8.4. Reversal of anticoagulation
Total Formulary
ANDEXANET ALFA (ONDEXXYA) (infusion)
Restrictions:
Restricted to use only on the advice of a Consultant Haematologist for the reversal of anticoagulation in adults treated with a direct factor Xa inhibitor where there is life-threatening or uncontrolled bleeding. In addition, use should be in accordance with the local protocol (in development).
IDARUCIZUMAB
Restrictions:
See Prescribing Notes below.
Prescribing Notes:
Restricted to specialist use only when rapid reversal of anticoagulation effect of dabigatran is required for emergency surgery/ urgent procedures or in life-threatening or uncontrolled bleeding in line with national guidance.