4.3. Antidepressant drugs
4.3.1. Tricyclic and related antidepressant drugs
4.3.2. Monoamine-oxidase inhibitors
Restrictions:
Restricted to patients who have failed to respond to first line antidepressants.
Restrictions:
Restricted to patients who have failed to respond to first line antidepressants.
Restrictions:
Restricted to specialist initiation only. Restricted to patients who have failed to respond to first line antidepressants.
4.3.3. Selective serotonin re-uptake inhibitors
Prescribing Notes:
Fluoxetine 20mg capsules are the preferred presentation in NHSGGC. Other strengths (e.g. 10mg, 60mg capsules) should not be prescribed routinely.
4.3.4. Other antidepressant drugs
Restrictions:
Restricted to psychiatrist initiation only as a third line therapy for major depressive episodes. The SMC has not recommended its use for generalised anxiety disorders.
Restrictions:
The immediate release preparation is restricted to use as third line agent for depression. The MR preparation is restricted to initiation on the advice of a consultant only. The CSM have advised that venlafaxine should not be used in children and adolescents under 18 years of age. The treatment of moderate to severe generalised social anxiety disorder/social phobia has not been accepted for use by SMC and is non-Formulary.