Greater Glasgow and Clyde Medicines

Formulary Search Results for: PONATINIB

8.1.5 Other antineoplastic drugs - View Category

Total Formulary
Specialist Only
PONATINIB (tablets)

Restrictions:

Restricted to specialist use in accordance with regional protocol for the indications listed in the Prescribing Notes below

Prescribing Notes:

Chronic myeloid leukaemia (CML):

The treatment of chronic phase, accelerated phase or blast phase chronic myeloid leukaemia (CML) in adults:

  • resistant to dasatinib or nilotinib
  • who are intolerant to dasatinib or nilotinib and for whom subsequent treatment with imatinib is not clinically appropriate
  • who have the T215 mutation

Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL)

The treatment of Philadelphia chromosome positive acute lymphoblastic leukaemia in adults:

  • who are resistant to dasatinib, intolerant of dasatinib and for whom subsequent treatment with imatinib is clinically appropriate
  • with the T3151 mutation

To access the regional protocol click here 

BNF Link