NHS Greater Glasgow & Clyde Area Drug and Therapeutics Committee
Greater Glasgow and Clyde Prescribing
  • Key to symbols

6 Endocrine system

6.4 Sex hormones

6.4.1 Female sex hormones

6.4.1.1 Oestrogens and HRT

Preferred list
ELLESTE SOLO

Prescribing Notes:

Contains estradiol 1mg.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/38344.htm#_38344

FEMOSTON

Prescribing Notes:

Available as 1/10 and 2/10 strengths. Contains estradiol and dydrogesterone.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/32805.htm

EVOREL SEQUI

Prescribing Notes:

Combination of Evorel® 50 patches (containing estradiol) and Evorel® Conti patches (estradiol and norethisterone acetate).

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/119687.htm#_119687

KLIOVANCE

Prescribing Notes:

Estradiol and norethisterone acetate.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/74032.htm

ELLESTE - DUET CONTI

Prescribing Notes:

Estradiol and norethisterone acetate.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/38343.htm#_38343

FEMOSTON CONTI

Prescribing Notes:

Estradiol and dydrogesterone.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/32805.htm

EVOREL CONTI

Prescribing Notes:

Estradiol and norethisterone acetate.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/119687.htm#_119687

TIBOLONE

Prescribing Notes:

Used for the short-term treatment of symptoms of oestrogen deficiency, tibolone is not suitable for use in the pre-menopausal stage or within 12 months of the last menstrual period (unless being treated with gonadotrophin releasing hormone analogues).

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/4330.htm

ELLESTE - DUET

Prescribing Notes:

Available as estradiol 1mg or 2mg with norethisterone 1mg.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/38343.htm#_38343

EVOREL

Prescribing Notes:

Transdermal patch containing estradiol. Available in 25, 50, 75 and 100 micrograms/24hour strengths.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/65812.htm#_65812

Total Formulary
ESTRADIOL (OESTROGEL) (GEL)

Restrictions: Restricted to patients who fail to tolerate oral or patch preparations.

Prescribing Notes:

Strength: 0.6%

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/31364.htm#_31364

RALOXIFENE HYDROCHLORIDE

Restrictions: Restricted to specialist initiation. Restricted to use in patients for whom bisphosphonates are contraindicated or not appropriate.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/73961.htm

SEE BNF

Restrictions: The following HRT preparations are non-formulary: Angeliq®

6.4.1.2 Progestogens

Preferred list
Total Formulary
ULIPRISTAL ACETATE (ESMYA) (tablets)

Restrictions:

The treatment of moderate to severe symptoms of uterine fibroids in adult women is restricted to the following MHRA advice:

  • intermittent treatment of moderate to severe symptoms of uterine fibroids in women of reproductive age who are not eligible for surgery
  • one course of pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age
  • treatment is to be initiated and supervised by a physician experienced in the diagnosis and treatment of uterine fibroids

Please refer to MHRA information prior to initiation.

BNF Link: https://www.medicinescomplete.com/#/content/bnf/_287099787?hspl=uliprista

6.4.2 Male sex hormones and antagonists

Preferred list
Total Formulary
DUTASTERIDE

Restrictions: Restricted to specialist initiation.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/127920.htm

TESTOSTERONE

Restrictions:

All testosterone preparations are restricted to specialist initiation.  In addition, testosterone gel is restricted to use on the recommendation of consultant endocrinologists, urologists and oncologists.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/4361.htm

6.4.3 Anabolic steroids

Total Formulary
NANDROLONE DECANOATE

Restrictions: Restricted to specialist use only.

BNF Link: http://www.medicinescomplete.com/mc/bnf/current/4379.htm